What does this procedure involve?

Haploidentical hematopoietic stem cell transplantation (HSCT) uses a half-matched family donor, such as a parent or sibling, to replace a patient's diseased bone marrow. The Beijing protocol combines a conditioning regimen with enhanced immunosuppression and graft manipulation to reduce rejection and graft-versus-host disease. Over 45–60 days, stem cells are collected from the donor, processed, and infused into the patient, followed by close monitoring for engraftment.