Who is a good candidate for it?

This combined approach is primarily indicated for patients with locally advanced cancers—such as cervical, prostate, head and neck, or certain gynecological malignancies—where the disease is confined to the region but not surgically removable. Contraindications include distant metastases, prior pelvic radiation that precludes further exposure, active infection at the insertion site, or severe comorbidities that make general anesthesia or chemotherapy unsafe. A thorough evaluation by an oncologist is essential to confirm suitability.