What are the risks and recovery expectations?

Common risks include transient headache, back pain, or mild fever following lumbar puncture, which usually resolve within 24–48 hours. Serious complications such as infection, allergic reaction, or neurological injury are rare but possible. Recovery is ongoing; most patients experience no downtime beyond the day of injection and can resume daily activities the next day. Functional improvements, if any, may take weeks to months to become noticeable, and the goal is to slow disease progression rather than cure ALS.