Who is a good candidate for it?

Ideal candidates are patients with histologically confirmed, non-metastatic nasopharyngeal carcinoma, typically Stage II–IVa (AJCC staging). Good candidates have adequate kidney function (creatinine clearance ≥60 mL/min), normal blood counts, and no severe hearing loss, as cisplatin can be ototoxic. Contraindications include distant metastases, poor performance status (ECOG >2), significant organ dysfunction, or prior radiation to the head and neck. Each patient should undergo a multidisciplinary evaluation including MRI, PET-CT, and dental assessment before starting treatment.